I am using ITK library to get a mesh from a 3D image, the 3D image is a volume of slices. I get the mesh using itk::BinaryMask3DMeshSource . But I need to get its physical coordinate for each mesh node and I don’t know how to do it. I know how to obtain with ITK the physical coordinate of a voxel in a image using the TransformIndexToPhysicalPoint function. But when I have a mesh like this or an ITK::Mesh I don’t know how to do it. I need to know if there is any relationship between the nodes of the mesh and the voxels in the image to find the physical coordinates or some way to do it.