Hi, thanks for your answer but this example uses itk :: BinaryMask3DMeshSource. In my previous question Previous question I asked how to get the physical coordinates of the mesh. As you told me according to the comments and the code seems to be that the coordinates of the mesh are physical coordinates but when I assign the GetOutput () method of itk :: BinaryMask3DMeshSource object to an ITK :: Mesh and I access the nodes and the cells coordinates, both are still in CT image coordinates and not physical coordinates. Maybe I’m doing something wrong but I don’t know.