Dear ITK forum Members,
All our registrations are performed using Simple ITK.
T1 weighted image is registered with SRI24 atlas (240,240,155) as a template (1st image) and with MNI152 (197,233,189) atlas (2nd image). 2nd image is re-registered with SRI24 again (3rd image).
After registration, we observed that the tumor location is changing in SRI (1st image) and MNI (2nd image) registration for the same patient T1-weighted image. Could you please guide us why the tumor location is changing in SRI and MNI registered images?
In all these examples voxel volume is fixed that is 1 mm^3. However, non-zero voxel volumes are different for different template references for the same patient T1-weighted image as shown below.
Non-zero brain volume of SRI registered T1 image (1st Image): 1512233
Non-zero brain volume of MNI registered T1 image (2nd Image): 793562
Non-zero brain volume of MNI to SRI registered T1 image (3rd Image): 1710923
The main concern is that why the tumor location is changing with different reference template? Why there is a change in volume between 1st and 3rd image?
Your help will be highly appreciated.
Thank you so much.
Best regards,
Sunita