Registation of two vascular images using Python Simple ITK

Hi,

I would like to register two vascular images of the same modality but with different dynamics. I played a lot with the image registration metrics (correlation, mutual information and correlation) with optimizer gradient descent, yet didn’t succeed. Here is an example (I uploaded the fixed and moving images):

Is there a better solution suited for such images?
Note that those images are actually different frames of a cine acquisition.

fixed.nii (259.6 KB)

moving.nii (259.6 KB)

Thanks!

Anatole