# Use BRAINSFit in a Python in-house software

**URL:** https://discourse.itk.org/t/use-brainsfit-in-a-python-in-house-software/6283
**Category:** Beginner Questions
**Tags:** itk, registration, python
**Created:** [November 5, 2023, 4:44pm UTC](https://discourse.itk.org/t/use-brainsfit-in-a-python-in-house-software/6283 "2023-11-05T16:44:40Z")
**Posts on this page:** 2
**Page:** 1

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### Author: ![Icron1](https://discourse.itk.org/user_avatar/discourse.itk.org/icron1/32/3754_2.png) [@Icron1](https://discourse.itk.org/u/Icron1)
#### Post date: [November 5, 2023, 4:44pm UTC](https://discourse.itk.org/t/use-brainsfit-in-a-python-in-house-software/6283/1 "2023-11-05T16:44:40Z")

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Hello dear community,

I am looking to use the BRAINSFit registration algorithm in a custom Python software to align cerebral MRIs. Is it possible to implement it in a Python-based software without using Slicer (which is excellent but I cannot use for my project)?

I have already tried several alternative algorithms, including Elastix and its SimpleITK version, but I have not been able to find settings that yield as good performance on the brain.

Thank you very much for your help.  
Loïc

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### Author: ![dzenanz](https://discourse.itk.org/user_avatar/discourse.itk.org/dzenanz/32/1093_2.png) [@dzenanz](https://discourse.itk.org/u/dzenanz)
#### Post date: [November 6, 2023, 1:31pm UTC](https://discourse.itk.org/t/use-brainsfit-in-a-python-in-house-software/6283/2 "2023-11-06T13:31:33Z")

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You could [build it standalone](https://github.com/BRAINSia/BRAINSTools#building), and then call it from Python via `subprocess.run` or something similar.