# Registratrion mpMRI prostate

**URL:** <https://discourse.itk.org/t/registratrion-mpmri-prostate/6442>\
**Category:** Algorithms\
**Tags:** registration\
**Created:** [February 15, 2024, 8:20am UTC](https://discourse.itk.org/t/registratrion-mpmri-prostate/6442 "2024-02-15T08:20:46Z")\
**Posts on this page:** 2\
**Page:** 1

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**Author:** ![Nathalie\_M](https://discourse.itk.org/user_avatar/discourse.itk.org/nathalie_m/32/3909_2.png) [@Nathalie\_M](https://discourse.itk.org/u/Nathalie_M)\
**Post date:** [February 15, 2024, 8:20am UTC](https://discourse.itk.org/t/registratrion-mpmri-prostate/6442/1 "2024-02-15T08:20:46Z")

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Hi,

I would like to register a T2w image (640x640x23) with a DWI (and ADC) MR image (116x228x25) of the prostate. The latter has a different size as it has been acquired using zoom. Origin of both images are (0,0,0).

I tried several ITK codes, but did not succeed to register both images.

In the end, I would like to apply this transformation on a segmentation mask as this segmentation has been created based on the T2w image, but I would like to project this on both the DWI and the ADC image.

Can somebody help me with this?

Many thanks!

 ![image](https://discourse.itk.org/uploads/default/original/2X/d/d68cff753fe22a8ef4562184a9842fb241f1ed15.png)

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**Author:** ![zivy](https://discourse.itk.org/user_avatar/discourse.itk.org/zivy/32/1726_2.png) [@zivy](https://discourse.itk.org/u/zivy)\
**Post date:** [February 15, 2024, 2:13pm UTC](https://discourse.itk.org/t/registratrion-mpmri-prostate/6442/2 "2024-02-15T14:13:34Z")

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Hello @Nathalie_M,

Before you continue writing code, please familiarize yourself with the ITK registration framework, and registration in general (likely what you are encountering is an issue with registration initialization).

Try using [Slicer’s registration functionality](https://slicer.readthedocs.io/en/latest/user_guide/registration.html) before writing any code. [This paper](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451374/) may be somewhat related to what you want to acomplish.