# 3D multi-modal medical image registration using user defined function for similarity metric computation

**URL:** https://discourse.itk.org/t/3d-multi-modal-medical-image-registration-using-user-defined-function-for-similarity-metric-computation/5064
**Category:** Beginner Questions
**Tags:** registration, python, simpleitk
**Created:** [June 7, 2022, 10:09am UTC](https://discourse.itk.org/t/3d-multi-modal-medical-image-registration-using-user-defined-function-for-similarity-metric-computation/5064 "2022-06-07T10:09:04Z")
**Posts on this page:** 2
**Page:** 3

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### Author: ![blowekamp](https://discourse.itk.org/user_avatar/discourse.itk.org/blowekamp/32/79_2.png) [@blowekamp](https://discourse.itk.org/u/blowekamp)
#### Post date: [September 9, 2022, 12:15pm UTC](https://discourse.itk.org/t/3d-multi-modal-medical-image-registration-using-user-defined-function-for-similarity-metric-computation/5064/42 "2022-09-09T12:15:23Z")

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How much memory does your laptop have?

I see the DEBUG build type being used. Those binaries are very large, and much if the information is not useful unless you are debugging SimpleITK. Does a Release build succeed?

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### Author: ![debapriya](https://discourse.itk.org/letter_avatar_proxy/v4/letter/d/bc79bd/32.png) [@debapriya](https://discourse.itk.org/u/debapriya)
#### Post date: [September 10, 2022, 3:41pm UTC](https://discourse.itk.org/t/3d-multi-modal-medical-image-registration-using-user-defined-function-for-similarity-metric-computation/5064/43 "2022-09-10T15:41:02Z")

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Yes, I could configure ITK and SimpleITK successfully with Release build.  
Thank you @blowekamp

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